Tonic clonic status epilepticus.

Tonic clonic status epilepticus.

Oxaliplatin-Induced Tonic-Clonic Seizures

Oxaliplatin is a common chemotherapy drug used for colon and gastric cancers. Common side effects are peripheral neuropathy, hematological toxicity, and allergic reactions. A rare side effect is seizures which are usually associated with posterior reversible leukoencephalopathy syndrome (PRES). A 50-year-old male patient presented with severe abdominal pain. CT scan of the abdomen showed acute ...

Painful generalised clonic and tonic-clonic seizures with retained consciousness.

Two patients in whom consciousness and memory were retained during bilateral clonic or tonic-clonic seizures are reported on, and three patients reported on previously are reviewed. Ictal semiology differed from myoclonic and supplementary motor seizures, which are other seizure types characterised by bilateral motor movements and retained awareness. In the two new patients ictal pain was a pro...

Tonic status epilepticus in patients with idiopathic generalized epilepsy.

RATIONALE Tonic status epilepticus (TSE) in patients with idiopathic generalized epilepsy (IGE) is not well recognized. The objective of this study is to report episodes of TSE in patients with IGE. METHODS We retrospectively reviewed the clinical and EEG evaluation of three IGE patients who presented TSE. RESULTS The three patients had mainly clinical features of IGE, but had developed, in...

Status epilepticus enhances tonic GABA currents and depolarizes

*Authors contributed equally 8 Running title: Status epilepticus alters dentate basket cell tonic inhibition 9 Abstract 37 Temporal lobe epilepsy is associated with loss of interneurons and inhibitory dysfunction in the 38 dentate gyrus. While status epilepticus (SE) leads to changes in granule cell inhibition, whether 39 dentate basket cells critical for regulating granule cell feed-forward an...